2 Nitro Express is a centerfire rifle cartridge developed by Eley Brothers and introduced in 1905.
2 Nitro Express is a rimmed, bottlenecked cartridge designed for use in single shot and double rifles.
Introduced in 1905, some writers have stated this cartridge never achieved the popularity it deserved because of the arrival of the .375 H&H Magnum seven years later.
2 Nitro Express is considered suitable for use for hunting all thin-skinned African or Indian game.
2 Nitro Express as a splendid cartridge, stating it was "ideally suited for use in doubles and single-loaders".