The Japanese title of the manga was 009ノ1, or "Zero Zero Ku-no-ichi", a pun on kunoichi (female ninja) and a reference to the main character's espionage occupation.

In June 2013, it was announced the manga would be adapted into a live-action film entitled 009-1: The End of the Beginning to be directed by Koichi Sakamoto, and starring Mayuko Iwasa.

In the final episode, there are two homages to Gerry Anderson television shows involving the Moon, an Eagle Transport from Space: 1999 and SHADO Mobiles from UFO.

A 12-episode anime series was produced by Ishimori Entertainment and XeNN Studios in partnership with Aniplex and first broadcast on TBS in Japan in late 2006.

Anime News Network's Theron Martin said the anime series "carries much of the style and flavor of Ishinomori's other iconic works like Kamen Rider and Kikaider" and noted "the series emphasizes Mylene's sex appeal by offering healthy and regular doses of fan service, although it leaves the most graphic parts to the imagination."

[1] Writing for Mania Entertainment, Chris Beveridge said 009-1 has "a good sense of pacing and style to it, going over the top in some ways but also keeping itself rather grounded in others.

"[10] Bryan Morton from Mania Entertainment described it as "James Bond with women, Najica with no panties (no not in that sense), a cold-war Ghost in the Shell - sort of."