The building was created in 1934–1937 by prominent Russian architects Andrey Kryachkov and Vitaly Maslennikov.

The building was originally conceived as a high-profile residential complex for the Soviet elite and arranged for 100 well-appointed apartments (hence the name).

The initial exterior design was substantially complicated in the process, for architect Maslennikov added facade elements themed after the works of French architect Auguste Perret.

At the Exposition Internationale des Arts et Techniques dans la Vie Moderne in Paris on December 11, 1937, the project, along with other works by Kryachkov, was awarded the 1st degree diploma, a gold medal, and a Grand Prix.

[4] In various years there lived Gersh Budker (physicist), Eugeny Meshalkin (cardiologist), Vladimir Mysh (surgeon), Alexander Tikhonov (biathlete), Yevgeny Mravinsky (conductor), Nikolai Cherkasov (actor), Nikolai Simonov (actor), Vasili Merkuryev (actor).