The 10th Separate Special Purpose Brigade (Russian: 10-я отдельная бригада специального назначения) is a spetsnaz military formation of the Russian Federation subordinate to the Spetsnaz GRU.

[1] The unit was formed in 1962 during the formation of the first special forces brigades of the Soviet Union.

At the time it was garrisoned in Pervomaiske, Crimean Oblast, Ukrainian SSR.

[2] After the fall of the Soviet Union in 1991 the unit was transferred to Ukraine where it was reformed into an airborne regiment.

In 2002 it was decided to establish the unit once again in Russia and this time it was garrisoned in Molkino.