The British 12th Destroyer Flotilla, or Twelfth Destroyer Flotilla, was a naval formation of the Royal Navy from November 1915 to March 1919 and again from September 1939 to 2 July 1943.

The flotilla was first formed in November 1915 and was assigned to the Grand Fleet.

[1] Between 31 May and 1 June 1916 it was present at the Battle of Jutland then commanded by Captain Anselan J.

[2] It remained with the Grand Fleet until November 1918 and was disbanded in March 1919.

[1] In September 1939 the flotilla was re-established and allocated to the Western Approaches Command and stationed at Portland till December 1939 when it was reassigned to the Home Fleet till May 1941 when its ships were dispersed among other formations.