This condition has been detected in multiple patients, all of whom consumed Mediator, a drug manufactured by the French pharmaceutical firm Servier, intended for diabetes treatment and weight loss.

Several of her colleagues collaborate on this, but the contribution of research scientist Dr. Antoine Le Bihan is especially significant.

However, when presenting their findings to AFSSAPS, the French regulatory agency for health products, their research is intensely scrutinized by Servier's representatives, and they're unsuccessful in getting Mediator removed from the market.

Irene gets support from her family, a reporter from Le Figaro, Anne Jouan, an AFSSAPS member, Catherine Haynes, and an informant from CNAM, the national health insurance fund.

The Hollywood Reporter's Leslie Felperin cited the "outsize but empathic central performance" by star Sidse Babett Knudsen in the role of Frachon and the director's ability to handle the film's "intellectually rigorous storytelling" and many characters.