1655 Malta plague outbreak

The outbreak appeared in Kalkara and some cases were reported in Żabbar and the urban area around the Grand Harbour.

The plague spread to other family members in Żabbar, and physicians were informed of the possibility of a contagious disease.

Some cases later appeared in the urban area around the Grand Harbour: in Valletta, Birgu, Senglea and Bormla.

Their house and its contents were burnt down, and a cordon sanitaire was imposed on the town of Żabbar.

When the disease appeared in the other Grand Harbour settlements, similar restrictions on movement were imposed and through these measures the outbreak was successfully contained.