1840 Democratic National Convention

Van Buren is the only major party presidential nominee since the ratification of the Twelfth Amendment to seek election without a running mate.

Dragged down by the unpopularity of the Panic of 1837, Van Buren was defeated by the Whig Party's ticket in the 1840 presidential election.

Decentralized power and states' rights pervaded each and every resolution adopted at the convention, including those on slavery, taxes, and the possibility of a central bank.

[3][4] Regarding slavery, the Convention adopted the following resolution:Resolved, That congress has no power under the Constitution, to interfere with or control the domestic institutions of the several states, and that such states are the sole and proper judges of every thing appertaining to their own affairs, not prohibited by the Constitution: that all efforts of the abolitionists or others, made to induce congress to interfere with questions of slavery, or to take incipient steps in relation thereto, are calculated to lead to the most alarming and dangerous consequences, and that all such efforts have an inevitable tendency to diminish the happiness of the people, and endanger the stability and permanency of the Union, and ought not to be countenanced by any friend to our political institutions.

Van Buren remains the only major party presidential nominee since the passage of the Twelfth Amendment to seek election without a running mate.