This was the first season the league expanded, as Indiana and Iowa began competing for the conference title.
The 1900 Minnesota Golden Gophers and Iowa Hawkeyes football teams tied for the conference championship.
Iowa, under head coach Alden Knipe, compiled a 7–0–1 record and led the conference in scoring offense with an average of 38.9 points per game.
The 1900 Wisconsin Badgers, under head coach Philip King, placed third in the conference, compiled an 8–1 record (its only loss being to Minnesota by a 7–6 score), shut out seven of nine opponents, and led the conference in scoring defense with an average of 1.2 points allowed per game.
In 1900, an All-Western football team was selected by Caspar Whitney (CW) in Outing magazine as follows:[7] No Western Conference players received first-team All-America honors in 1900.