The 1910 VFL season was the 14th season of the Victorian Football League (VFL), the highest-level senior Australian rules football competition in Victoria.

The season featured ten clubs and ran from 30 April to 1 October, comprising an 18-match home-and-away season followed by a four-week finals series featuring the top four clubs.

Carlton won the minor premiership by finishing atop the home-and-away ladder with a 15–3 win–loss record.

In 1910, the VFL competition comprised ten teams of 18 on-the-field players each, with no "reserves", although any of the 18 players who had left the playing field for any reason could later resume their place on the field at any time during the match.

Once the 18 round home-and-away season had finished, the 1910 VFL Premiers were determined by the specific format and conventions of the amended "Argus system".