The 1916 VFL Grand Final was an Australian rules football game contested between the Carlton Football Club and Fitzroy Football Club, held at the Melbourne Cricket Ground in Melbourne on 2 September 1916.

It was the 19th annual Grand Final of the Victorian Football League, staged to determine the premiers for the 1916 VFL season.

The match, attended by 21,130 spectators, was won by Fitzroy by a margin of 29 points, marking that club's sixth premiership victory.

The 1916 season was played by only 4 teams, Carlton, Collingwood, Richmond and Fitzroy, owing to the absence of many of the players who were fighting in World War I. Carlton ended the home and away season with 10 wins from 12 games and were minor premiers.

Carlton defeated Richmond by 3 in the other Semi Final.