The 1918 East Tyrone by-election was held on 3 April 1918.
The by-election was held due to the resignation of the incumbent Irish Parliamentary Party MP, William Redmond.
It was won by the Irish Parliamentary candidate Thomas Harbison.
The by-election was the last in a short string of by-elections where it seemed that the more moderate nationalists were regaining ground from Sinn Féin before being virtually wiped out in the 1918 United Kingdom general election in Ireland.
This article about a by-election to the Parliament of the United Kingdom in Ireland is a stub.