1921 Buffalo All-Americans season

Since Philadelphia was subject to blue laws in the commonwealth of Pennsylvania, the Quakers had to play their games on Saturdays, as opposed to the Sundays used by the APFA, including Buffalo.

Five, including Wray, chose to stay with the Quakers, blaming the Buffalo management for "blowing the whistle."

Buffalo was able to hire players from the Detroit Heralds, who folded midseason, to complete their roster.

Chicago defeated Buffalo, who did not have the services of the Heralds players it had borrowed (they were playing against the Detroit Maroons the same day), in the rematch by a score of 10–7.

According to Pro Football Reference, the following players saw game action as members of the 1921 Buffalo All-Americans.