1921 Rock Island Independents season

The team failed to improve on their previous record against league opponents of 6–2–2, winning only four games.

[2] The Independents entered their second season in the American Professional Football Association (APFA) with an air of positivity.

Eight league games were tentatively scheduled for 1921 — four at home and four on the road, concluding with a November 27 match-up with the Columbus Panhandles at Rock Island's Douglas Park.

[3] Ultimately, only seven league games would be managed, with just two of these contests at home, both weakly attended.

There were two future members of the Pro Football Hall of Fame on the roster — tackle Ed Healey and quarterback Jimmy Conzelman, both members of the hall's second class, inducted in September 1964.