This was the last victory for an American constructor in a major European race until the Ford GT40's triumph at the 1966 24 Hours of Le Mans as well as in a Grand Prix race until the Dan Gurney's win with the Eagle car at the 1967 Belgian Grand Prix.

The US was represented by eventual winner Duesenberg, and France by Ballot and Mathis, the latter of which was based in Strasbourg, which was part of Germany before World War I.

[1][3] As the first major Grand Prix since the War, it was decided that engine regulations should match those of the Indianapolis 500 with a 3-litre maximum.

[1] By the end of the second lap, the order was more established, with Murphy leading Boyer, Chassagne, and DePalma.

Guyot had a large gap back to third place, but when he stopped for fuel and water on lap 28, he was unable to restart.