The 1921 San Diego East-West Christmas Classic was a college football postseason bowl game between the Centre Praying Colonels and the Arizona Wildcats.
Southern Intercollegiate Athletic Association champion Centre was undefeated going into this game.
Arizona was in their first bowl game, led by Harold "Nosey" McClellan and his 124 points during the scoring.
Centre led 18-0 at the half as Arizona was held to no first downs in two quarters of play.
[2] Centre would play in the 1922 Dixie Classic a week later, but lose in the game that started the 12th man tradition.