Ohio was won decisively by the Republican Party candidate, incumbent President Calvin Coolidge with 58.33 percent of the popular vote.

The economic boom and good feelings of the Roaring Twenties under popular Republican leadership virtually guaranteed Calvin Coolidge an easy win in the state against the conservative Southern Democrat John Davis, who had little appeal in Northern states like Ohio where his reticence on the Ku Klux Klan was opposed by Catholics.

[2] Ohio did possess a very powerful Ku Klux Klan organization which had swept the state's elected offices in the previous year, but had a sufficiently large Catholic population that its delegates to the Democratic National Convention demanded an anti-KKK plank.

[3][4] Davis was also handicapped by a complete lack of support from local Democratic officeholders, despite efforts to campaign in the state in October.

Nonetheless, La Follette easily outpolled Davis in the major urban areas of northern Ohio, and carried the city of Cleveland and many precincts elsewhere in Cuyahoga County on the strength of labor union support.