The election matched incumbent Democrat Walter M. Pierce against Republican Isaac L. Patterson and Independent candidate H. H. Stallard, who ran on an anti-Prohibition platform.

[1] However, soon after the 1922 election, the Klan faded in power due in part to internal struggles and changing public sentiment.

[1] Now running for re-election in 1926, Pierce won his party's primary for re-election in 1926 over Louise Palmer Weber, one of many anti-Prohibition candidates that year who ran on a platform of repealing or modifying laws regarding the regulation of alcoholic beverages in Oregon.

[2][3] In their primary, Republicans nominated former state senator I. L. Patterson, who had chaired Calvin Coolidge's successful election campaign in Oregon,[4] over Jay H. Upton and W. A.

[5] In the general election, Patterson cruised to a 12-point victory over the incumbent Pierce, with Stallard earning more than 5% of the vote.