The 1927 Targa Florio was a Grand Prix motor race held on the 108 km Medio Circuito Madonie in Sicily, Italy on the 24th of April 1927.
Materassi drove the fastest lap of the race (1 hour 25 minutes 48.8) and took the lead, while Alfieri Maserati and Conelli also moved up the order to second and third respectively.
Fagioli, also in a Salmson, was second in the 1100cc race, but had to push his car over the finish line due to a broken fuel pipe.
Maggi also crashed his Maserati, but much to the surprise of his team was able to get back to the pits, around an hour later than expected, where he too would retire.
Alfieri Maserati lost time but held third followed by Boillot, while Joaquín Palacio was able to overtake Dubonnet for fifth place.
Heinrich Eckert and Salvatore Marano both completed the full distance of five laps, but were not classified as they exceeded the maximum allowed time of 9 hours.