Wyoming was won by the Democratic nominee, the 44th Governor of New York, Franklin D. Roosevelt, running with John Nance Garner, the 39th Speaker of the United States House of Representatives, with 56.07 percent of the popular vote, against the incumbent Republican President Herbert Hoover and Vice President Charles Curtis, with 40.82 percent of the popular vote, a 15.3% margin of victory.

Roosevelt promised to enact a serious of legislative proposals, collectively called The New Deal, to end the Great Depression.

Roosevelt campaigned cautiously, trying to minimize gaffes while keeping the attention on his opponent, who was so unpopular that wherever he went, he often had items thrown at him, and was publicly opposed by numerous prominent Republicans such as Senators Bronson Cutting and Henry Wallace.

[3] Though both campaigns spent heavily on radio, Roosevelt employed it more effectively, using it to craft a persona that voters believed cared about them, while also hiding his paralysis due to Polio.

Roosevelt's liberal big government policies remain a large part of the Democratic Party's platform in the modern era, with many of the programs he enacted, such as Social Security remaining in effect and popular with voters, so much so to the point where most politicians avoid mentioning changing it at all.