A pressure of 911.9 hPa (26.93 inHg) was observed in Muroto, making the typhoon the strongest ever recorded to impact Japan at the time.

Turning north by September 24, the system deepened and impacted the Aleutian Islands; it was last noted the following day over western Alaska.

Regarded at the time as the "second-greatest catastrophe of modern Japan" after the 1923 Great Kantō earthquake, the storm left parts of Osaka in ruins.

[5][6][7] Though surpassed less than a year later during the 1935 Labor Day hurricane in the Florida Keys,[8] it remains the lowest value ever observed in mainland Japan and the third-lowest throughout the country.

After another brief stint over water, the storm made its next landfall directly over Kobe, Hyōgo Prefecture, just 30 km (19 mi) west of Osaka City.

[2] Pronounced frontal features, a characteristic of extratropical cyclones, developed late on September 21, with a cold front extending south toward the Philippines.

[2] Surface weather analyses depict the system continuing east, crossing the International Date Line (180°) by September 23.

[12] Winds up to Force 10—89 to 102 km/h (55 to 63 mph)—on the Beaufort scale affected parts of the Aleutians and a pressure of 964 mbar (hPa; 28.47 inHg) was observed near 48°00′N 160°30′W / 48°N 160.5°W / 48; -160.5.

[14] Contemporaneously called the "second-greatest catastrophe of modern Japan",[15] and the "worst typhoon in a generation",[3] the storm wrought tremendous damage in Shikoku and southern Honshu, with areas in and around Osaka suffering the brunt of its impact.

[4] The city of Osaka was crippled by the typhoon, electricity was completely lost, the water supply network sustained significant damage, and communications were disrupted.

[20] The Sotojima hospital for leprosy was destroyed; 260 patients are believed to have drowned after the building collapsed amid rising water and gale-force winds.

[25] Significant damage took place in Aichi, Gifu, Kyoto, Nagano, Nagasaki, Tokushima, Tottori, Wakayama, and Yamanashi prefectures.

[21][24] Immediately following the typhoon's tremendous impact, the Japanese military was deployed to Osaka before nightfall on September 21 and water was being trucked in.

[21] Three destroyers from the Kure Naval District, loaded with medical equipment and other essentials, were deployed to assist in relief work.

[26] During an October 5 cabinet meeting, Minister of Education Genji Matsuda recommended schools to be built with steel in light of the large number of children killed.

[4] According to a 2010 report by the Central Disaster Prevention Council, if a storm identical to the 1934 Muroto typhoon were to strike in the modern day, it would kill approximately 7,600 people.