In its first season under head coach Frank Leahy, Notre Dame compiled an 8–0–1 record, outscored opponents by a total of 189 to 64, and was ranked No.
Quarterback Angelo Bertelli led the team on offense and went on to win the Heisman Trophy in 1943.
End Bob Dove was a consensus first-team player on the 1941 All-America team; he was later inducted into the College Football Hall of Fame.
Guard Bernie Crimmins was also selected by Collier's and Liberty magazines as a first-team All-American.
This college football 1940s season article is a stub.