The 1942 Saint Louis Billikens football team was an American football team that represented Saint Louis University as a member of the Missouri Valley Conference (MVC) during the 1942 college football season.
In its third season under head coach Dukes Duford, the team compiled a 4–5 record and was outscored by a total of 215 to 110.
[1] Saint Louis was ranked at No.
154 (out of 590 college and military teams) in the final rankings under the Litkenhous Difference by Score System for 1942.
[2] The team played its home games at Edward J. Walsh Memorial Stadium in St. Louis.