The 1943 VFL season was the 47th season of the Victorian Football League (VFL), the highest level senior Australian rules football competition in Victoria.

As in 1942, only eleven of the league's twelve clubs competed, with Geelong remaining in recess due to travel restrictions during World War II.

The premiership was won by the Richmond Football Club for the fifth time, after it defeated Essendon by five points in the 1943 VFL Grand Final.

In 1942, the VFL competition consisted of eleven teams of 18 on-the-field players each (Geelong did not field a team due to wartime rail and road transport restrictions), plus one substitute player, known as the 19th man.

Melbourne shared the Punt Road Oval with Richmond as their home ground, South Melbourne shared Princes Park with Carlton as their home ground and St Kilda played their home games at Toorak Park (this was possible because there was no VFA competition in 1943); Footscray, however, was able to return to Western Oval, as it was vacated by the defence authorities after a year.