The Cardinals defeated the Brooklyn Dodgers in a regular season best-of-three tiebreaker, for the National League title, after both teams finished their 154-game schedules with identical 96–58 records.
The Cardinals defeated the Red Sox, four games to three, capturing their sixth championship in franchise history, since their previous in 1944.
Many notable ballplayers returned from their military service this season, following the end of World War II, such as Joe DiMaggio, Stan Musial, and Ted Williams.
Opening Day took place on April 16, featuring all sixteen teams, continuing the trend from the previous season.
Due to the Brooklyn Dodgers and St. Louis Cardinals finishing with the same record of 96–58, a best-of-three tie-breaker was scheduled, to be considered an extension of the regular season.