The 1948–49 Panhellenic Championship was the 15th season of the highest football league of Greece.
The clubs that participated were the champions from the 3 founding football associations of the HFF: Athens, Piraeus and Macedonia.
Panathinaikos won the championship, due to a better goal ratio than Olympiacos.
The point system was: Win: 3 points - Draw: 2 points - Loss: 1 point.