Two weeks after the previous World Championship race, the Dutch Grand Prix, the teams headed to the Circuit de Spa-Francorchamps in Belgium.

The Maserati factory team added Johnny Claes and a third Argentine, Onofre Marimón, to their lineup of Juan Manuel Fangio and José Froilán González, while Felice Bonetto missed this race.

Jean Behra, whose injuries prevented his participation at Zandvoort, returned for Gordini alongside Maurice Trintignant, and the American pairing of Harry Schell and Fred Wacker, while HWM called on the services of Paul Frère (as they had done the previous year) in their third car in addition to regulars Peter Collins and Lance Macklin.

The Maseratis were definitely capable of matching the Ferraris for sheer speed – Juan Manuel Fangio put in a record-shattering practice lap of 117 mph, breaking Ascari's run of five consecutive pole positions (excluding the Indianapolis 500).

[1] Alberto Ascari, who had taken his ninth consecutive World Championship victory (ignoring the Indy 500), already had a large lead in the points standings.