The race took place from 19–23 November, and was run from Tuxtla Gutiérrez, Chiapas, to Ciudad Juárez, Chihuahua, over 8 stages and 3,077 kilometres (1,912 mi).
[2] For the 1953 race, the existing Sports and Stock classes were both subdivided into Large and Small groups, giving four categories in which to compete.
During pre-race runs of the route at much safer speeds, Felice Bonetto and Piero Taruffi, winner of the 1951 edition of the race, painted warning signals on the road to remind themselves of particular hazards.
Entering the village of Silao, he encountered rough pavement at excessive speed and impacted a building, killing him instantly.
[4] As a result of Guido Mancini and Fabrizio Serena di Lapigio finishing in fourth place, in their Ferrari 375 MM Pinin Farina Berlinetta, they secured three points for Ferrari, thereby increasing the Maranello marque points lead over Jaguar, giving them the 1953 World Championship for Manufacturer title.