It was played on Monday, August 3, at the Los Angeles Memorial Coliseum in Los Angeles, California, home of the Los Angeles Dodgers of the NL,[1][2] and was a 5–3 victory for the American League.

[3][4] This was the second of two All-Star Games played in 1959, the first was on Tuesday, July 7, in Pittsburgh, Pennsylvania, also an NL city.

[5][6] The first Midsummer Classic held on the West Coast,[2] it was also the first of only two All-Star Games not played in July; the other was in 1981 following a lengthy players' strike.

Players in italics have since been inducted into the National Baseball Hall of Fame.

Umpires: Bill Jackowski, Home Plate (NL); Charlie Berry, First Base (AL); Tony Venzon, Second Base (NL); Bill Summers Third Base (AL); Ken Burkhart, Left Field (NL); Hank Soar, Right Field (AL)