The 1959 NAIA World Series was the third annual tournament hosted by the National Association of Intercollegiate Athletics to determine the national champion of baseball among its member colleges and universities in the United States and Canada.

[1] The tournament was played at Kokernot Field in Alpine, Texas, near the campus of Sul Ross State College.

Western Washington player Roger Repoz was named tournament MVP.

The tournament field decreased in size from the 1958 event, shrinking from twelve back to eight teams.

Furthermore, the format of the tournament changed from single-elimination to double-elimination.