The 1959 SANFL Grand Final was an Australian rules football match played at Adelaide Oval on 3 October 1959 to conclude the 1959 SANFL season.

Port Adelaide beat West Adelaide 87 to 77 to claim their 20th SANFL premiership.

[1] This was Port Adelaide's sixth consecutive SANFL Grand Final victory, setting a senior Australian rules football record for most consecutive premierships.

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