The 1965–66 Maltese First Division was the 51st season of top-tier football in Malta.
The season started on 16th October 1965 and ended on 23rd February 1966.
It was entirely played on Manoel Island football ground.
[2] It was contested by 6 teams, and Sliema Wanderers F.C.
won the championship for the 18th time, the third in a row.