1965 American Football League season

The season also saw a change of television address as the games moved from ABC to NBC.

The season ended when the Buffalo Bills defeated the San Diego Chargers in the AFL Championship game.

The next season, the AFL would join the NFL to form the AFL-NFL World Championship game, known today as the Super Bowl.

The Bills led the Eastern Division from start to finish, ending five games ahead of the 5–8–1 Jets.

In the Western Division, San Diego had three potential wins cancelled out when they were tied by Kansas City (10–10), Boston (13–13) and Buffalo (20–20), but their 9–2–3 finish (.818) was well ahead of Oakland's 8–5–1 record (.615).