1972 United States House of Representatives elections in South Carolina

Incumbent Republican Congressman Floyd Spence of the 2nd congressional district, in office since 1971, was unopposed in his bid for re-election.

Incumbent Democratic Congressman William Jennings Bryan Dorn of the 3rd congressional district, in office since 1951, defeated Republican challenger Ray Ethridge.

Incumbent Democratic Congressman James R. Mann of the 4th congressional district, in office since 1969, defeated Republican challenger Wayne N. Whatley.

Incumbent Democratic Congressman Thomas S. Gettys of the 5th congressional district, in office since 1964, defeated Republican challenger B. Leonard Phillips.

Republican Edward Lunn Young defeated Democrat John Jenrette in the general election.