The 1978 NCAA Division II men's basketball tournament involved 32 schools playing in a single-elimination tournament to determine the national champion of men's NCAA Division II college basketball as a culmination of the 1977-78 NCAA Division II men's basketball season.
It was won by Cheyney State of Pennsylvania and Cheyney's Andrew Fields was the Most Outstanding Player.
*denotes tie Location: Cope Hall Host: Cheyney State College Location: Volpe Center Host: Merrimack College Location: Florida Tech Fieldhouse Host: Florida Technological University Location: Matador Gymnasium Host: California State University, Northridge Location: Lantz Arena Host: Eastern Illinois University Location: Towson Center Host: Towson State University Location: Hammons Center Host: Southwest Missouri State University Location: Brown County Veterans Memorial Arena Host: University of Wisconsin at Green Bay *denotes each overtime played Location: Hammons Center Host: Southwest Missouri State University *denotes each overtime played † Florida Tech is now known as University of Central Florida, as opposed to the current Florida Institute of Technology.