Season started in August 1980 and finished in May 1981.
[1] In Montenegrin Republic League 1980-81 participated 14 teams.
Among the clubs which didn't play on previous season were three best sides from lower tier - Arsenal, Jezero and Titeks.
[2] The title won Mogren, with five points more than Titeks[3] On season 1980–81, four Montenegrin teams played in higher leagues of SFR Yugoslavia.
[4] Budućnost participated in 1980–81 Yugoslav First League, while three other teams (Sutjeska, OFK Titograd and Lovćen) played in 1980–81 Yugoslav Second League.