The 1980 Chicago Cubs season was the 109th season of the Chicago Cubs franchise, the 105th in the National League and the 65th at Wrigley Field.

The Cubs finished sixth and last in the National League East with a record of 64–98.

Infielders Coaches Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.

= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games played; AB = At bats; H = Hits; Avg.

= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts