The Tuscan regional election of 1980 took place on 8 June 1980.

Election was held under proportional representation with provincial constituencies where the largest remainder method with a Droop quota was used.

To ensure more proportionality, remained votes and seats were transferred at regional level and calculated at-large.

After the election Mario Leone (Italian Socialist Party), the incumbent President of the Region, formed a new government with the Italian Communist Party.

In 1983 a government crisis occurred as the relationship between the Communists and the Socialists had become tense at the national level.