The 1981 Italian Indoor Open, also known as the Bologna Open or Bologna Indoor, was a men's tennis tournament played on indoor carpet courts that was part of the 1981 Volvo Grand Prix circuit and took place in Bologna, Italy.

It was the seventh and last edition of the tournament and was held from 16 November through 22 November 1981.

Third-seeded Sandy Mayer won the singles title.

[3] Sandy Mayer defeated Ilie Năstase 7–5, 6–3 Sammy Giammalva Jr. / Henri Leconte defeated Tomáš Šmíd / Balázs Taróczy 7–6, 6–4