The 1981 WTA German Open was a women's tennis tournament played on outdoor clay courts at the Rot-Weiss Tennis Club in West Berlin in West Germany that was part of the Toyota Series Category 3 tier of the 1981 WTA Tour.

It was the 12th edition of the tournament and was held from 18 May through 24 May 1981.

Eighth-seeded Regina Maršíková won the singles title and earned $20,000 first-prize money.

[1][2] Regina Maršíková defeated Ivanna Madruga 6–2, 6–1 Rosalyn Fairbank / Tanya Harford defeated Sue Barker / Renáta Tomanová 6–3, 6–4