It was carrying 18 champion horses, for an equestrian competition in Miami, for Indianapolis for the 10th Annual Pan American Games.

The pilots managed to dodge several skyscrapers in the city, including the Mexicana Airlines Headquarters tower and the World Trade Center.

The aircraft flew under a pedestrian bridge and smashed into vehicles, killing some motorists instantly and horribly injuring others.

The tail of the plane separated from its main body and smashed into a three-story building, while the rest of the aircraft skidded and impacted the crowded Tras Lomita restaurant.

At least 7 people inside the plane were found alive, including American pilots Frederick Moore and Robert Banty, and the load master.

Teresa Marquez of the federal Emergency Rescue Service said at least seven people on the ground were severely burned and taken to two hospitals.

At least 25 vehicles were rammed and caught fire due to the crash, and a further 44 people on the ground were killed, bringing the death toll to nearly 50.