The 1988 NCAA Division I Women's Lacrosse Championship was the seventh annual single-elimination tournament to determine the national championship for Division I National Collegiate Athletic Association (NCAA) women's college lacrosse.
The championship game was played at Walton Field in Haverford, Pennsylvania during May 1988.
The Temple Owls won their second championship by defeating the Penn State Nittany Lions in the final, 15–7.
All NCAA Division I women's lacrosse programs were eligible for this championship.
In the end, 6 teams contested this tournament, an increase of two from the previous year.