The 1988 Campeonato Nacional was Chilean football league top tier's 56th season.
Cobreloa was the tournament's champion, winning its fourth title.
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Deportes Iquique qualified for the final due to its better League head-to-head results (2-1 & 0-0) Colo-Colo qualified for the final due to its better League head-to-head results (3-1 & 0-0) Colo-Colo qualified for the 1989 Copa Libertadores