It is the home stadium of Chilean football team Audax Italiano.

Faith No More performed at the stadium on October 30, 2009 as part of their The Second Coming Tour.

The stadium has also been used for concerts by Travis Scott, The Weeknd, System of a Down, Primus, Rage Against the Machine, The Mars Volta, The Black Eyed Peas, Green Day, Rammstein, Dua Lipa, Harry Styles, Post Malone, Def Leppard and Mötley Crüe.

In 2007, La Florida was selected as a venue for the 2008 FIFA U-20 Women's World Cup.

In order to comply with FIFA standards, the old stadium was torn down and an entirely new venue was built.