The 1990–91 Wake Forest Demon Deacons men's basketball team represented Wake Forest University as a member of the Atlantic Coast Conference during the 1990–91 NCAA men's basketball season.

The team was led by 2nd year head coach Dave Odom, and played their home games at LJVM Coliseum in Winston-Salem, North Carolina.

Wake Forest finished in a tie for third in the ACC regular season standings with an 8–6 conference record.

5 seed in the Southeast region of the NCAA tournament – the school's first appearance in seven years.

[1] This season formed the foundation of a school-record seven straight NCAA tournament appearances between 1991 and 1997.