He took a six-second victory over Italian driver Alessandro Nannini driving a Benetton B190 who was just two seconds in front of Senna's Austrian teammate Gerhard Berger.
Larrousse had scored enough points during the previous two half-seasons to be relieved of the requirement to pre-qualify, and could automatically join the rest of the field in the main qualifying sessions from here on.
[1] Here at Hockenheim, Ligier were comfortably first and second in the one-hour session, with Philippe Alliot outpacing team-mate Nicola Larini in their Ford-powered JS33Bs.
Those missing out on pre-qualification included fifth-placed Gabriele Tarquini in the other AGS, a second slower than his team-mate, and Roberto Moreno, sixth in the EuroBrun.
Also ending his involvement at this early stage for the ninth Grand Prix in a row was Claudio Langes in the other EuroBrun, ahead only of Bruno Giacomelli, who was again a far distant last in the Life.
The Ferraris of Prost and Nigel Mansell were over 1.5 seconds slower (with the Englishman complaining of a down on power engine compared to his team mate), and the Williams-Renaults of Riccardo Patrese and Thierry Boutsen occupying the 3rd row.
[2] McLaren also introduced a new aerodynamic cowling cover for the MP4/5B at Hockenheim designed to lessen the buffeting effect on the drivers heads by diverting air to the sides of the car.
The order of the top 6 remained the same until the 11th lap when Piquet made an attempt to pass Patrese in the Williams, but had to take an escape road and was overtaken for 6th by teammate Nannini as a result.
Philippe Alliot was disqualified because marshals helped his Ligier JS33B rejoin the race after being blocked by the spinning Dallara 190 of Emanuele Pirro.