The 1990 Iowa State Cyclones football team represented Iowa State University as a member of the Big Eight Conference during the 1990 NCAA Division I-A football season.
Led by fourth-year head coach Jim Walden, the Cyclones compiled an overall record of 4–6–1 with a mark of 2–4–1 in conference play, tying for fourth place in the Big 8.
Iowa State played home games at Cyclone Stadium in Ames, Iowa.
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