The 1999 UEFA Regions' Cup was the first UEFA Regions' Cup.

It was held in Italy and won by the Veneto team from the host nation, which beat Spain's Madrid 3–2, after extra time, in the final.

The 32 teams entered were drawn into eight groups of four, with the following countries hosting each group's matches: The winners of each group qualified for the final tournament.

Notes: Notes: Italy was chosen to host the final tournament, with matches being played from 31 October to 5 November 1999.

UEFA Regions' Cup