It is subordinated to the Air Force General Command and has seen intensive action throughout the War in Donbas and Russian invasion of Ukraine.

[12] On 27 October 2014, a soldier of the detachment (Kostyshyn Yaroslav Myroslavovych) was killed by shelling on Avdiivka by separatist forces near the Donetsk Airport.

[18] Moreover two personnel from the detachment (Vasyl Vasyliovych Petrenko[19][20] and Popovych Denys Grigoryovych[21]) were also killed during the battle in addition to the destruction of four APCs, three BMPs, seven Ural-4320s, one Kraz, four Rapier guns and damage to two tanks of the Mechanized Brigade.

[23] On 13 April 2015, during one of the attacks by separatists on the Zenit position near Avdiivka, the fragment of a 120-mm mine shell hit the ammunition boxes in the dugout and the resulting explosion killed five soldiers of the detachment (Oleksiy Anatoliyovych Vovchenko,[24] Dmytro Ivanovych Hura,[25] Vasyl Mykolayovych Putanenko,[26][27] Oleksandr Mykolayovych Tyshchenko[28] and Bohdan Anatoliyovych Goncharenko[29]) who were taking cover.

Following the Russian invasion of Ukraine, the detachment was reformed into the 1st Combined Rifles Brigade of the Ukrainian Air Force in February 2023 and the reformation was officially confirmed on 26 June 2023,[30] the brigade was already serving on the frontlines in Donetsk Oblast and also saw combat during the 2023 Ukrainian counteroffensive for which fifteen personnel of the regiment received state awards.