It is located at Magazine Road within the city's Central Business District (CBD), next to Komtar and Prangin Mall, and is linked to both buildings via overhead bridges.

Upon its completion, it competes directly against the adjacent Prangin Mall and has since attracted a variety of well-known international fashion brands, including H&M, Skechers, Cotton On and Victoria's Secret.

In addition, there are a number of restaurants, cafes and beverage outlets within 1st Avenue Mall, including Texas Chicken, Starbucks, Subway, Kenny Rogers Roasters, The Chicken Rice Shop, Seoul Garden, Sushi King, Tealive, A&W, Taco Bell, J.CO Donuts, Pacific Coffee and OldTown White Coffee.

1st Avenue Mall's location at the heart of George Town, right next to the Rapid Penang bus terminal in Komtar, makes it easily accessible to locals and tourists alike.

One can take the free-of-charge Rapid Penang CAT bus from anywhere within George Town's UNESCO World Heritage Site to get to 1st Avenue Mall.